Types of Bioinformatics Analyses

The following are common categories of analyses performed in modern genomics and systems biology.

1. Proteomics

Proteomics is the large-scale study of proteins.

2. Metabolomics

Metabolomics focuses on the complete set of small molecules within a biological sample.

3. RNA-Seq

RNA Sequencing is used to quantify RNA molecules and gene expression.

4. Single-cell Analysis

Single-cell analysis explores gene expression at the individual cell level.

5. Genome Assembly and Annotation

Genome assembly and annotation reconstructs complete genomes from short or long sequencing reads and labels genes, regulatory regions, and functional elements.

6. Regulatory Genomics

Regulatory genomics explores how DNA and other factors control gene expression patterns.

7. Variant Calling and Haplotype Analysis

Variant calling and haplotype analysis identifies base substitutions (Single Nucleotide Variants), helping identify mutations.

Example SNV:

C A GCTTA G

T GCTTA T

A GCTTA G

A A GCTTACG G

Blue = reference base (G), red = alternate base (T).